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Reduced glutathione is the main source of thiol groups in the vast majority of living cells, plays an important role in maintaining the appropriate redox state of thiol groups in proteins, and is a key antioxidant in animal cells

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Treatment with FG-4592/EVs diminishes the apoptosis of tubular cells and suppresses the activation of the NF-κB pathway caused by hypoxia, consequently lowering the secretion of pro-inflammatory The role of inflammatory cytokines, like IL-6, from impaired tubular cells in offering therapeutic advantages for AKI [160]